Ahr cell atlas

Author: qzlg

August undefined, 2024

WebApr 23, 2024 · Intestinal immune dysfunction is involved in the onset of Crohn’s disease (CD). Dendritic cells (DCs), antigen-presenting cells, play a key role in the maintenance of intestinal immune homeostasis. The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor widely expressed in various immune cells, including DCs. Although … WebAug 26, 2024 · a AHR, ARNT, CYP1A1, CYP1B1, IDO1, and PML mRNA expression levels were determined by scRNA-Seq in ciliated and secretory epithelial cells from healthy or COVID-19 patients. b Ingenuity pathway...

Regulation of the immune response by the aryl hydrocarbon receptor

WebJul 5, 2024 · Current evidence suggests that AhR may affect NK cells via regulating inflammatory signaling pathways to induce immune surveillance . Based on these data, … WebJun 2, 2008 · The aryl hydrocarbon receptor (AhR) was discovered almost 30 years ago as a specific binding site for the halogenated polycyclic aromatic hydrocarbon, 2,3,7,8 … chino for women

Cell atlas - AHR - The Human Protein Atlas

WebAHR Cell type Cell type Class Cardiovascular Cell type HCASMC NA NA Attributes by original data submitter Sample source_name HCASMC_AHR ChIP-Seq cell line Human Coronary Artery Smooth Muscle Cells (HCASMC) tissue coronary artery genotype/treatment dioxin (TCDD) 10nM chip antibody AHR antibody (Santa Cruz, sc-5579) Sequenced … WebMay 3, 2024 · The aryl hydrocarbon receptor (AhR) is the only ligand-activated member of the PER-ARNT-SIM (bHLH-PAS) superfamily of transcription factors ().It is overexpressed and chronically active in HNSCC (6, 7), breast cancer (8–11), glioblastoma (12, 13), and other cancers (14–17).Chronically active AhR enhances cancer “stem-ness” and drives … WebNov 15, 2024 · The aryl hydrocarbon receptor (AHR) is a ligand binding-transcription factor of the basic helix-loop-helix family regulating multiple cellular functions such as … chino flights

AHR aryl hydrocarbon receptor - NIH Genetic Testing Registry …

Cell line - AHR - The Human Protein Atlas

WebDec 17, 2024 · Our single cell atlas facilitated an analysis of the molecular cross-talk between tumor cells and each of the stromal cell types. To this end, ... AHR, and TBX3 and the periportal ID1, TBX15, and SOX4, as well as zonated surface markers (Appendix Fig S8B and C). The high-resolution hepatocyte zonation map forms a resource for exploring … WebJun 2, 2008 · Within the last decade, AhR was found to have a basic helix-loop-helix and function as a ligand-activated transcription factor. Located in the cytoplasm of most cells, AhR forms a receptor... chino fit body boot campWebThe aryl hydrocarbon receptor (AhR) is an important nuclear transcription factor that is best known for mediating toxic responses by adjusting numbers of metabolism-related … chino freeport

"http://chip-atlas.org/view?id=SRX8358262 " - Ahr cell atlas

Ahr cell atlas

Cell atlas - AHR - The Human Protein Atlas

WebNov 2, 2016 · Clinical resource with information about AHR, An atlas of genetic influences on human blood metabolites., Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption., Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption., … WebAug 28, 2024 · The transcription factor AHR (aryl hydrocarbon receptor) drives the expression of genes involved in detoxification pathways in cells exposed to pollutants and other small molecules. Moreover, AHR supports transcriptional programs that promote ribosome biogenesis and protein synthesis in cells stimulated to proliferate by the …

Did you know?

WebMar 27, 2024 · Objective: Aryl hydrocarbon receptor (AhR) is a transcription factor. It is reported that AhR is associated with non-small cell lung cancer (NSCLC), but the mechanisms underlying this relationship remain unclear. Therefore, we investigated the role of AhR in NSCLC to elucidate the underlying …

WebHUMAN PROTEIN ATLAS INFORMATIONi. Summary of RNA expression based on cell line data from the DepMap portal and cell line data generated within the Human Protein … WebAHR (HGNC Symbol) Synonyms: bHLHe76: Description: Aryl hydrocarbon receptor (HGNC Symbol) Entrez gene summary: The protein encoded by this gene is a ligand-activated …

WebMar 15, 2024 · Thus, given our previously observed differences in the ARNT isoform 1:3 ratio between normal human T cells and human T cell neoplasms , as well as the critical nature of AhR signaling in T cell function , we turned our attention to assessing whether the ARNT isoforms might distinctively regulate AhR activity. Interestingly, three regulatory ... WebThe aryl hydrocarbon receptor (AhR) is a ligand-dependent transcriptional factor expressed by many cell types, particularly in barrier tissues, such as the gastro-intestinal tract. AhR …

WebApr 14, 2024 · 我国科学家绘制出人类胚胎器官发生时期单细胞图谱. 中国海洋大学等研究团队合作绘制了人类胚胎早期器官发生的单细胞转录组图谱。. 该研究成果于近日发表在《Nature Cell Biology》杂志上，题为：A single-cell transcriptome atlas profiles early organogenesis in human embryos ...

WebOct 25, 2024 · AHR is a basic helix-loop-helix family of ligand-activated transcription factors originally discovered for its induction of the P450 pathway in response to environmental … graniteridge school wisconsinWebCell atlas. Showing subcellular location of AHR. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More … chino from deftonesWebNov 15, 2024 · AHR is a ligand-activated transcription factor that is well-studied for its role in signaling that contributes to cellular metabolism of environmental toxins and more recently, is being recognized for its importance in endogenous cell functions. granite ridge school wiWebOct 5, 2024 · The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor best known for its role in sensing xenobiotics and regulating the expression of genes … chinofungin velemenyekWebMar 1, 2024 · From the viewpoint of the cancer cell, Ahr is well known as a promoter of tumor development and acts as a key regulator of proliferation, apoptosis, metabolism, angiogenesis, and other processes (previously reviewed in detail [6]).Indoleamine-2,3-dioxygenase 1 (IDO1) is a metabolic enzyme that converts the essential amino acid … chino from ontarioWebFeb 8, 2024 · AhR directs macrophage polarization. Hezaveh et al. identified a key role for AhR in tumor macrophage function in pancreatic cancer, with AhR suppressing inflammatory T cell infiltration and promoting growth. AhR was activated by gut microbiome-produced tryptophan metabolites and human disease showed association of … chinofungin stift patikákWebNov 13, 2024 · A reference atlas of human cell types is a major goal for the field. Here, we set out to generate single-cell atlases of both gene expression (this study) and chromatin … chino from charm city kings