Circrnas: a regulator of cellular stress

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August undefined, 2024

WebFeb 10, 2024 · We cannot rule out that the DE lncRNAs/circRNAs identified under the cellular stresses tested have cell-type specificity. Although we have found a series of DE lncRNAs and circRNAs in cellular stress responses, investigations about functions of individual ncRNA of interest, and the molecular mechanism are required. WebFeb 8, 2024 · The brain is anatomically and functionally divided into distinct regions consisting of diverse cell types with complex transcriptome architectures [].Early studies have shown that circRNA expression is significantly different and highly enriched in the brains of wide range of mammals including mice, primates, and humans [10, 11].The …

Roles of circular RNAs in immune ... - Cell Death & Disease

WebOct 20, 2024 · Circular RNAs (circRNAs), a type of non-coding RNA, are single-stranded circularized molecules characterized by high abundance, evolutionary conservation and cell development- and tissue-specific expression. A large body of studies has found that circRNAs exert a wide variety of functions in diverse biological processes, including cell … the pulse agency

CircRNAs: a regulator of cellular stress - Taylor & Francis

WebSimilarly, some circRNAs also remain in the nucleus and are localized near the beginning of the transcription of their parental genes, possibly acting as positive regulators of Pol II … WebFeb 10, 2024 · We cannot rule out that the DE lncRNAs/circRNAs identified under the cellular stresses tested have cell-type specificity. Although we have found a series of … WebApr 8, 2024 · Through the regulation of GBM cell proliferation, invasion, metastasis, angiogenesis, and apoptosis, certain circRNAs have been identified as tumor suppressors or promoters in the evolution of GBM. circ-PRKCI , circ-CPA4 , circ-CDC45 , circ-SCAF11 , and circ-POSTN are some of the circRNAs that belong to this group . The purpose of … significance of jesus choosing 12 disciples

Circrnas: a regulator of cellular stress

(PDF) Specific expression and functions of circular RNAs

WebJan 1, 2024 · Results: Genome-wide circRNA profiling by circRNA sequencing (circRNA-seq) revealed that a large number of circRNAs were induced by estrogen, and further … Web2 days ago · Background As a diverse and abundant class of endogenous RNAs, circular RNAs (circRNAs) participate in various biological processes including cell proliferation and apoptosis. Nevertheless, few researchers have investigated the role of circRNAs in muscle development in cultivated pigs. Results In this study, we used RNA-seq to construct …

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WebJan 17, 2024 · Europe PMC is an archive of life sciences journal literature. WebMay 21, 2024 · Circular RNAs (circRNAs) are covalently closed loop structures that lack free 3’ and 5’ ends. 1 CircRNAs have long been understudied, and their regulatory potential has yet to be fully...

WebJul 27, 2024 · Currently, the understanding of circRNAs in the mechanism of oxidative stress is limited. In this review, we described the relationship between oxidative stress … WebSep 3, 2024 · In some situations, these databases are beneficial for research studying the functions and mechanisms of circRNAs; however, there is currently no database available that describes the transcriptional regulation of circRNAs, which limits researchers’ ability to easily obtain transcriptional regulation information about circRNAs, including TF ...

WebMicroRNAs (miRNAs) are linear single-stranded non-coding RNAs oligonucleotides, widely distributed in cells, playing a key role as regulators of gene expression at post … WebFischer, J.W. and Leung, A.K. (2024) CircRNAs A Regulator of Cellular Stress. Critical Reviews in Biochemistry and Molecular Biology, 52, 220-233. ... These circRNAs have several potential modes of action, some of which serve as microRNAs sponges shown in Table 1, protein binding RNAs, cellular transports, transcriptional regulators and ...

WebJan 11, 2024 · CircRNAs have tissue- and developmental stage-specific expression patterns, owing to their abundance, stability and diverse expression profiles, and likely play a pivotal role in various biological activities and regulatory pathways; for instance, a few studies revealed that circRNAs could serve as miRNA sponges and thereby impair …

WebMar 10, 2024 · Epithelial-to-mesenchymal transition (EMT) is a dynamic program of cell plasticity aberrantly reactivated in cancer. The crosstalk between tumor cells and the … the pulse can be palpatedWebJan 17, 2024 · Although the mechanism modulating circRNA levels during stress remains unclear, circRNAs are shown to be regulated during biogenesis, degradation, and … the pulse brdbWebApr 10, 2024 · Empty Cell: circRNAs Effect on endothelium; cZNF292: Regulates EC orientation and rearranges focal adhesion organisation under laminar flow: circHIPK3: ... Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. Proc Natl Acad Sci U S A, 116 (26) (2024), pp. 12974-12979. the pulsar mapWebJun 26, 2024 · Circular RNAs (circRNAs), as a novel class of endogenously expressed non-coding RNAs (ncRNAs), have a high stability and often present tissue-specific … the pulse apartments memphis tnWebJul 27, 2024 · Circular RNAs in the Regulation of Oxidative Stress Front Pharmacol. 2024 Jul 27;12:697903. doi: 10.3389/fphar.2024.697903. ... In this review, we described the relationship between oxidative stress and circRNAs, the circRNAs related to oxidative stress, and the role of circRNAs in promoting or inhibiting the occurrence and … the pulse castWebFeb 24, 2024 · In the last decade, numerous circRNAs were discovered by virtue of the RNA-Seq technique. With the deepening of experimental research, circRNAs have brought to light the key biological functions and progression of human diseases. CircRNA ITCH has been demonstrated to be a tumor suppressor in numerous cancers, and recently it was … significance of jesus’ baptism reflectionWebJan 15, 2024 · Background/Aims: Circular RNAs (circRNAs), a type of RNA that is widely expressed in human cells, have essential roles in the development and progression of cancer. CircRNAs contain microRNA (miRNA) binding sites and can function as miRNA sponges to regulate gene expression by removing the inhibitory effect of an miRNA on its … the pulse blog