WebDec 2, 2024 · Compared to control animals, Cyp19-Cre;Nr5a1f/f cKO males showed normal fertility and testicular function. The Cyp17Cre/+;Nr5a1f/f cKO males had smaller testis, with drastically reduced Leydig cell volumes and impaired steroidogenesis, though their reproductive performance remained comparable to controls. WebAug 1, 2014 · For the Cyp19-Cre allele, female double heterozygotes ( Cited2∆LacZ/+ Cre+) were mated with Cited2flox/flox males, generating three control genotypes: Cited2+/flox Cre-; Cited2+/flox Cre+; Cited2∆LacZ/flox Cre-; and the conditionally deleted genotype Cited2∆LacZ/flox Cre+.
Expression of Cre recombinase in early diploid trophoblast cells of the
WebApr 17, 2012 · (B) Genotypic analysis of embryos derived from intercrosses of Tpbp-cre, Plfcre, Pl1cre, and Cyp19-cre with E2f7loxp/loxp;E2f8loxp/loxp mice. For the Tpbp-cre, Pl1cre, and Plfcre experiment, cre refers to the presence of cre allele in heterozygosity. (C) Representative PCR genotyping analyses of E2f7 and E2f8. WebWe conclude that the CYP19-Cre transgenic mouse developed here can be used in combination with conditional alleles to distinguish between embryonic and extra … mashed potatoes without dairy
KRAS G12D activates the RAF1/MEK/ERK1/2 and PI3K/AKT
WebThe CYP19A1Cre targets Cre recombinase selectively to ovarian granulosa cells for deleting floxed genes in these cells. Hemizygous: There is not phenotype of these mice. … WebMay 1, 2024 · The Cyp19-Cre 5912 founder line specifically expresses Cre recombinase at placental trophoblast precursor cells during the early stage of embryogenesis and shows minimal expression of Cre recombinase in fetal tissues (Wenzel and Leone, 2007), which allows us to examine the functionality of IL-6 in MIA model specifically in placental … WebAug 22, 2024 · Compared to WT, Cyp19-Cre females with YB-1-deficient placentas showed reduced implantation areas at GD8, 10 and 12; decreased placental areas and diameters at GD10 and 12; diminished placental ... hwy 29 short stop