Itsn1-s

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August undefined, 2024

Web3 jun. 2024 · Intersectin1 (ITSN1) is a highly conserved scaffold protein during evolution with multiple domains 12. ITSN1 gene frequently encodes two major isoforms referred to as … Web3 jun. 2024 · Our previous results had shown ITSN1-S could promote glioma development; however, the function of ITSN1-L remained unknown. In this study, we first confirmed …

Intersectin 1 is required for neuroblastoma tumorigenesis.

Web10 sep. 2010 · Intersectin1 (also called ITSN1) as a molecular linker in the central nervous system is well known as an important regulator of endocytosis and exocytosis. ITSN1 has two isoforms: ITSN1-l and ITSN1-s. In this study, we show that siRNA-mediated down regulation of ITSN1-s induced glioma cells apoptosis. Web28 okt. 2024 · ITSN1 gene (intersectin 1) is located on chromosome 21q22.11 and encodes a cytoplasmic membrane-associated protein involved in many cellular processes such as … michigan democratic primary

Alternative splicing-derived intersectin1-L and intersectin1-S exert ...

WebS. V. Pankivskyi, N. V. Senchenko, P. B. Busko et al. with proteins involved in clathrin-mediated endocytosis and actin cytoskeleton remodeling, as well as with components of some cell sig-naling cascades including MAPK-, PI3KC2β-, and JNK-mediated pathways [4]. ITSN1 and ITSN2 were found to be in-volved in oncogenesis. First, ITSN1 overex- Web27 apr. 2024 · Besides its well-established role in endocytosis, ITSN1-s is involved in the regulation of cell signaling and is implicated in tumorigenesis processes, although the … WebView ITSN1 mouse/human homology from Alliance Direct with: genes, location, sequences, associated human diseases michigan department natural resources hunting

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Muhtadi SULIMAN - Postdoctoral Researcher - INSERM …

WebHA-tagged ITSN1-S and myc-tagged ITSN1-L showed no interaction with SHIP1 (data not shown), but interact with SHIP2 (Fig. 1D and E), which is consistent to two-hybrid study (Fig. 1B). The similar results were obtained for ITSN2-S and 2-L which were also observed to associate with SHIP2 (data not shown). 3.2. Intersectin and SHIP2 associate ... WebAnti-ITSN1 antibody produced in chicken, affinity isolated antibody Catalog Number GW21428 Formerly listed as GenWay Catalog Number 15-288-21428, Intersectin-1 Antibody. Storage Temperature Store at –20 °C Synonyms: Intersectin 1 (SH3 domain protein); SH3 domain protein-1A; intersectin (SH3 domain protein 1A); human the north face junior beanieWeb19 feb. 2013 · Indeed, Hunter and colleagues demonstrated that overexpression of ITSN1-S in the forebrains of mice, particularly the striatum, resulted in sex-dependent decrease in locomotor activity in the transgenic animals . The level of ITSN1-S overexpression in the transgenic brains was comparable to the level of ITSN1-S observed in human DS patients. michigan dentures in redford

"Web23 jan. 2012 · ITSN1's transforming potential in vitro suggests that this scaffold protein may be involved in human tumorigenesis. Herein, we demonstrate that ITSN1 is expressed in primary human neuroblastoma tumors and tumor cell lines and is necessary for their in vitro and in vivo tumorigenic properties. " - Itsn1-s

Itsn1-s

Entry - *602442 - INTERSECTIN 1; ITSN1 - OMIM

Web28 sep. 2024 · Intersectin 1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which are highly regulated by alternative splicing. Our previous results showed that the two … WebResearch: Investigating the role of Intersectin-1 (ITSN1) in Tracheoesophageal (TE) Development using Esophageal Raft Cultures. Mentor: Vered Schacam-Silverberg PI: James M Wells

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WebINSERM UMR1231. déc. 2024 - aujourd’hui4 ans 5 mois. Dijon Area, France. My present postdoctoral position comparised a study of oro-sensorial perception of dietary lipids and the role of The lure of the lipids in the treatment of obesity in animals. I am used mouse model to investigated the downstream molecular pathways/candidates gene ... Web1 jan. 2024 · ITSN1-S is expressed in many tissues localizing throughout the cytoplasm and perinuclear regions [22]. Both ITSN1-S and ITSN2-S localize to clathrin-coated vesicles [22], [23] and ITSN1-S is also associated with small invaginations of the plasma membrane named caveolae [24].

http://genome.cse.ucsc.edu/cgi-bin/hgGene?hgsid=1606766419_Tg8e56cADHfATHzAGHYT5aIOZJxm&hgg_section_method_close=1 WebITSN1 has two major protein isoforms as a result of differential splicing: a long 200 KDa form (ITSN1-L); and a short 140 KDa form (ITSN1-S).

WebOptical Imaging; Developmental Neuroscience; Techniques in Neuroscience WebITSN1_ENST00000379960 AA mutation p.? (Unknown) CDS mutation c.*1878+115T>A (Substitution - intronic) Nucleotides inserted n/a Genomic coordinates GRCh38, 21:33818587..33818587, view Ensembl contig CDD n/a HomoloGene n/a Ever confirmed somatic? Yes Remark n/a Recurrent n/a Drug resistance n/a Alternative Ids

WebITSN1 ATP5O LINC00649 RN7SL740P AP000569.9 MRPS6 SLC5A3 RPS5P2 LINC00310 AP000318.2 KCNE2 AP000320.6 SMIM11A C21orf140 CMP21-97G8.1 AP000322.53 CMP21-97G8.2 KCNE1 SNORA11 RCAN1 Layered H3K27Ac Cons 100 Verts 4 _-0.5 _ Common dbSNP(155) Created Date: 4/10/2024 5:17:58 AM Title:

WebFor instance, Lnc-ITSN1-2 serve as ceRNA for IL-23R via sponging mir-125a in IBD. 19 In addition, circRNA_103765 functions as a ceRNA to promote DLL4-mediated cell apoptosis by decoying the miR-30 family in CD. 31 Therefore, the construction of the ceRNA to understand regulation mechanisms and explore potential biomarkers is essential. michigan democratic primary candidatesWeb2 apr. 2015 · We also found that the expression of ITSN1-S protein was essential to glioblastoma cell proliferation. Furthermore, through a series of expression constructs … the north face kaban charged backpackWebCompare Intersectin 1 (ITSN1) (NM_003024) Human Over-expression Lysate from OriGene Technologies on Biocompare.com. Welcome Guest. Sign In Register. Products. Popular Categories; Antibody Search; Biomolecules; Assay Kits; ... Phone: 1-888-267-4436 (U.S. only) / 301-340-3188 the north face kadın montWeb8 okt. 2024 · ITSN1-S contained a nuclear localization signal in residues 306–312 Most macromolecules contain nuclear localization signals (NLSs) and NESs for nuclear import … the north face kapcie męskieWeb8 jun. 2024 · ITSN1 has been identified as a Cdc42 specific GEF in in vitro studies [ 24, 25] and is one of several RhoGEFs showing a high frequency of alterations in some cancer types [ 26, 27 ]. The small molecule ZCL278 was identified by a high throughput virtual screen where candidates were docked into the ITSN1 binding groove of Cdc42 ( Figure 2 ). michigan department health \u0026 human servicesWeb12 apr. 2024 · ITSN1 and p38 MAPK enhance the c-Cbl effects on EGFR, either by disrupting the interaction of Spry2 with c-Cbl ... (LSRSTS 112) and only partially in Spry3 (LPQHLS 80), but is absent in Spry4. michigan department civil rightsWeb杨超，王重庆，陈颖，田巍，朱驹（第二军医大学药学院药物化学教研室，上海 200433）黏着斑激酶及其小分子抑制剂作为抗肿瘤药物的研究进展 michigan department of agriculture director